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Assay Detail

CHEMBL5250679

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human SK-MEL-28 cells harboring BRAF V600E mutant assessed as cell viability incubated for 72 hrs by crystal violet staining based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-MEL-28
Confidence 1 — Organism
Curated By Autocuration

Target

SK-MEL-28 (CHEMBL614919)
Type CELL-LINE
Organism Homo sapiens

Publication

Ferroptosis-related small-molecule compounds in cancer therapy: Strategies and applications.
Yin L, Liu P, Jin Y, Ning Z, Yang Y, Gao H.
Eur J Med Chem (2022) 244 : 114861 -114861
PubMed 36332549 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.62 5.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4303384 1 5.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4303384 IC50 = 2400.0 nM 5.62