Assay Detail
Binding
CHEMBL5250708
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of hedgehog signalling pathway in mouse NIH3T3 cells by Gli-Bla reporter assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Current approaches and strategies to identify Hedgehog signaling pathway inhibitors for cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.15 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473417 | VISMODEGIB | 4.0 | 1 | 8.15 |
| CHEMBL5274178 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473417 | VISMODEGIB | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL5274178 | — | IC50 | = | 0.005 | nM | - |