Assay Detail
Binding
CHEMBL5253273
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant PI3K p110alpha/p85 (unknown origin) incubated for 1 hr in presence of gamma[33P]ATP by scintillation counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design strategies, structure activity relationship and mechanistic insights for purines as kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3393066 | VS-5584 | 1.0 | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3393066 | VS-5584 | IC50 | = | 11.0 | nM | 7.96 |