Assay Detail
Binding
CHEMBL5253295
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MraY in Escherichia coli
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phospho-N-acetylmuramoyl-pentapeptide-transferase (CHEMBL3559642) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli |
Publication
Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage ϕX174 lysis protein E, and cationic antibacterial peptides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.10 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5279875 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5279875 | — | IC50 | = | 800.0 | nM | 6.10 |