Assay Detail
Functional
CHEMBL5253983
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human LAMA-84 cells overexpressing BCR/ABL assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LAMA-84 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
3-Aroyl-1,4-diarylpyrroles Inhibit Chronic Myeloid Leukemia Cell Growth through an Interaction with Tubulin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1642 | IMATINIB MESYLATE | 4.0 | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1642 | IMATINIB MESYLATE | IC50 | = | 100.0 | nM | 7.00 |