Assay Detail
Functional
CHEMBL5254149
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Antifungal activity against Candida albicans assessed as inhibition of extracellular acidification measured after 12 mins in presence of glucose
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Elucidation of antimicrobial activity and mechanism of action by N-substituted carbazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.04 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3359320 | — | — | 1 | 5.62 |
| CHEMBL5268677 | — | — | 1 | 5.05 |
| CHEMBL5286133 | — | — | 1 | 5.02 |
| CHEMBL5277475 | — | — | 1 | 5.01 |
| CHEMBL5287997 | — | — | 1 | 4.88 |
| CHEMBL4548520 | — | — | 1 | 4.65 |
| CHEMBL638 | VORICONAZOLE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3359320 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL5268677 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL5286133 | — | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL5277475 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL5287997 | — | IC50 | = | 13100.0 | nM | 4.88 |
| CHEMBL4548520 | — | IC50 | = | 22200.0 | nM | 4.65 |
| CHEMBL638 | VORICONAZOLE | IC50 | > | 75000.0 | nM | - |