Assay Detail
Functional
CHEMBL5255494
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HBV ayw1 infected in human HepG2.2.15 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2.2.15 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
2- and 3-Fluoro-3-deaza-1',6'-isoneplanocin: Synthesis and antiviral properties (including Ebola and Marburg).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.65 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 7.70 |
| CHEMBL5275097 | — | — | 1 | 6.37 |
| CHEMBL5279888 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5275097 | — | EC50 | = | 430.0 | nM | 6.37 |
| CHEMBL5279888 | — | EC50 | = | 1280.0 | nM | 5.89 |