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Assay Detail

CHEMBL5256018

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Yellow fever virus 17D infected in Huh-7 cells assessed as reduction in cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Yellow fever virus
Cell Type Huh-7
Confidence 1 — Organism
Curated By Autocuration

Target

Yellow fever virus (CHEMBL613731)
Type ORGANISM
Organism Yellow fever virus

Publication

The protein disulfide isomerase inhibitor 3-methyltoxoflavin inhibits Chikungunya virus.
Puhl AC, Fernandes RS, Godoy AS, Gil LHVG, Oliva G, Ekins S.
Bioorg Med Chem (2023) 83 : 117239 -117239
PubMed 36940609 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.43 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL601757 1 6.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL601757 EC50 = 370.0 nM 6.43