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Assay Detail

CHEMBL5256115

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Functional
Cytotoxicity against human SEM cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SEM
Confidence 1 — Organism
Curated By Autocuration

Target

SEM (CHEMBL4296493)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis and <i>in vitro</i> cytotoxicity evaluation of indolo-pyrazoles grafted with thiazolidinone as tubulin polymerization inhibitors.
Soni JP, Chilvery S, Sharma A, Reddy GN, Godugu C, Shankaraiah N.
RSC Med Chem (2023) 14 : 549 -562
PubMed 36970141 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.22 10.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4447541 1 10.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4447541 IC50 = 0.06 nM 10.22