Assay Detail
Binding
CHEMBL5256366
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Antagonist activity at 5-HT6 receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT<sub>6</sub> receptor interaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.60 | 9.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3286580 | IDALOPIRDINE | 3.0 | 1 | 9.08 |
| CHEMBL2220318 | — | — | 1 | 8.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3286580 | IDALOPIRDINE | Ki | = | 0.83 | nM | 9.08 |
| CHEMBL2220318 | — | Ki | = | 7.84 | nM | 8.11 |