Assay Detail

CHEMBL5256536

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiplatelet aggregation activity in Sprague-Dawley rat platelet rich plasma assessed as reduction in ADP-induced platelet aggregation

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Rattus norvegicus
Cell Type	Platelet
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Anagrelide: A Clinically Effective cAMP Phosphodiesterase 3A Inhibitor with Molecular Glue Properties.

Meanwell NA.
ACS Med Chem Lett (2023) 14 : 350 -361
PubMed 37077378 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	6.57	6.57

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL760	ANAGRELIDE	4.0	1	6.57

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL760	ANAGRELIDE	EC50	=	270.0	nM	6.57