Assay Detail
Binding
CHEMBL5257299
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SARS-CoV 3CL protease using 2-aminobenzoyl-SVTLQSG-Tyr(NO2)-R as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome coronavirus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.58 | 4.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243757 | — | — | 1 | 4.84 |
| CHEMBL397974 | — | — | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243757 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL397974 | — | IC50 | = | 48700.0 | nM | 4.31 |