Assay Detail
Functional
CHEMBL5257326
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Cytotoxicity against human MINO cells assessed as inhibition of cell proliferation incubated for 4 hrs by MTS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MINO |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.21 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5267172 | — | — | 1 | 5.43 |
| CHEMBL5279512 | — | — | 1 | 5.28 |
| CHEMBL5287303 | — | — | 1 | 5.23 |
| CHEMBL5290555 | — | — | 1 | 5.08 |
| CHEMBL5280637 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5267172 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL5279512 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL5287303 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL5290555 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL5280637 | — | IC50 | = | 9500.0 | nM | 5.02 |