Assay Detail
Functional
CHEMBL5257340
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Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 4 hrs by MTS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.30 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5267172 | — | — | 1 | 5.66 |
| CHEMBL5287303 | — | — | 1 | 5.34 |
| CHEMBL5279512 | — | — | 1 | 5.26 |
| CHEMBL5290555 | — | — | 1 | 5.17 |
| CHEMBL5280637 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5267172 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL5287303 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL5279512 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL5290555 | — | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL5280637 | — | IC50 | = | 8900.0 | nM | 5.05 |