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Assay Detail

CHEMBL5257571

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against rat MTLn3 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Rattus norvegicus
Cell Type MTLn3
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Artemisinin-Derived Dimers: Potent Antimalarial and Anticancer Agents.
Fröhlich T, Çapcı Karagöz A, Reiter C, Tsogoeva SB.
J Med Chem (2016) 59 : 7360 -7388
PubMed 27010926 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.33 7.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5279089 1 7.37
CHEMBL5283131 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5279089 IC50 = 43.0 nM 7.37
CHEMBL5283131 IC50 = 52.0 nM 7.28