Assay Detail
Binding
CHEMBL5257589
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DENV2 recombinant NS2B-NS3 protease expressed in Escherichia coli JM109 assessed as inhibition constant using acetyl-TTSTRR-para-nitroaniline as substrate preincubated for 10 mins followed by substrate addition measured after 120 mins by spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | dengue virus type 2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Progress and prospects on DENV protease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.81 | 4.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL205548 | — | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL205548 | — | Ki | = | 15430.0 | nM | 4.81 |