Assay Detail
Binding
CHEMBL5257948
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Inhibition of Bacterial MraY
9
Total Activities
9
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Nucleoside Derived Antibiotics to Fight Microbial Drug Resistance: New Utilities for an Established Class of Drugs?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.72 | 7.96 |
| Ki | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5284084 | — | — | 1 | 7.96 |
| CHEMBL5280148 | — | — | 1 | 6.13 |
| CHEMBL5268243 | — | — | 1 | 5.96 |
| CHEMBL277069 | — | — | 1 | 5.30 |
| CHEMBL5272682 | — | — | 1 | 5.20 |
| CHEMBL5274364 | — | — | 1 | 5.20 |
| CHEMBL20130 | — | — | 1 | 4.30 |
| CHEMBL5280253 | — | — | 1 | - |
| CHEMBL5284675 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5284084 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL5280148 | — | IC50 | = | 740.0 | nM | 6.13 |
| CHEMBL5268243 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL277069 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL5272682 | — | IC50 | = | 6250.0 | nM | 5.20 |
| CHEMBL5274364 | — | IC50 | = | 6250.0 | nM | 5.20 |
| CHEMBL20130 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL5280253 | — | Ki | = | 10.0 | ng/ml | - |
| CHEMBL5284675 | — | IC50 | = | 150000.0 | nM | - |