Assay Detail
Binding
CHEMBL5258032
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Inhibition of neutral endopeptidase (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Side Chain Cyclized Aromatic Amino Acids: Great Tools as Local Constraints in Peptide and Peptidomimetic Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.67 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50582 | — | — | 1 | 8.59 |
| CHEMBL49920 | — | — | 1 | 8.41 |
| CHEMBL299639 | — | — | 1 | 8.21 |
| CHEMBL51576 | — | — | 1 | 6.76 |
| CHEMBL287896 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50582 | — | IC50 | = | 2.6 | nM | 8.59 |
| CHEMBL49920 | — | IC50 | = | 3.9 | nM | 8.41 |
| CHEMBL299639 | — | IC50 | = | 6.1 | nM | 8.21 |
| CHEMBL51576 | — | IC50 | = | 175.0 | nM | 6.76 |
| CHEMBL287896 | — | IC50 | = | 400.0 | nM | 6.40 |