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Assay Detail

CHEMBL5258266

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-COV2 infected in african green monkey Vero E6 cells assessed as inhibition of viral replication incubated for 48 hrs by plague assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Cell Type Vero E6
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Arylnaphthalene Lignans with Anti-SARS-CoV-2 and Antiproliferative Activities from the Underground Organs of <i>Linum austriacum</i> and <i>Linum perenne</i>.
Tóth G, Horváti K, Kraszni M, Ausbüttel T, Pályi B, Kis Z, Mucsi Z, Kovács GM, Bősze S, Boldizsár I.
J Nat Prod (2023) 86 : 672 -682
PubMed 36857518 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.72 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL221190 DIPHYLLIN 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL221190 DIPHYLLIN IC50 = 1920.0 nM 5.72