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Assay Detail

CHEMBL5258707

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Binding
Inhibition of RAD51 (unknown origin) mediated homologous recombination
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA repair protein RAD51 homolog 1 (CHEMBL2034807)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and biological evaluation of DIDS analogues as efficient inhibitors of RAD51 involved in homologous recombination.
Demeyer A, Fonteneau L, Liennard M, Foyer C, Weigel P, Laurent AD, Lebreton J, Fleury F, Mathé-Allainmat M.
Bioorg Med Chem Lett (2023) 87 : 129261 -129261
PubMed 36990245 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1271993 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1271993 IC50 = 20000.0 nM 4.70