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Assay Detail

CHEMBL5259489

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SUDV infected in human HeLa cells assessed as reduction in viral cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Sudan ebolavirus
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

Sudan ebolavirus (CHEMBL5291667)
Type ORGANISM
Organism Sudan ebolavirus

Publication

An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the <i>Bunyavirales</i> Order.
Sparrow KJ, Shrestha R, Wood JM, Clinch K, Hurst BL, Wang H, Gowen BB, Julander JG, Tarbet EB, McSweeney AM, Ward VK, Evans GB, Harris LD.
ACS Med Chem Lett (2023) 14 : 506 -513
PubMed 37077387 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1236524 GALIDESIVIR 2.0 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1236524 GALIDESIVIR EC50 = 3000.0 nM 5.52