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Assay Detail

CHEMBL5259490

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Functional
Antiviral activity against Influenza A virus infected in dog MDCK cells assessed as reduction in viral cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the <i>Bunyavirales</i> Order.
Sparrow KJ, Shrestha R, Wood JM, Clinch K, Hurst BL, Wang H, Gowen BB, Julander JG, Tarbet EB, McSweeney AM, Ward VK, Evans GB, Harris LD.
ACS Med Chem Lett (2023) 14 : 506 -513
PubMed 37077387 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1236524 GALIDESIVIR 2.0 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1236524 GALIDESIVIR EC50 = 1000.0 nM 6.00