Assay Detail
Functional
CHEMBL5259506
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Yellow fever virus infected in human Huh-7 cells assessed as reduction in virus-induced cytopathic effect measured after 15 to 30 mins by neutral red based analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Yellow fever virus |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the <i>Bunyavirales</i> Order.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.50 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5273609 | — | — | 1 | 6.30 |
| CHEMBL5276564 | — | — | 1 | 5.44 |
| CHEMBL1236524 | GALIDESIVIR | 2.0 | 1 | 4.75 |
| CHEMBL5270241 | — | — | 1 | - |
| CHEMBL5275463 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5273609 | — | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL5276564 | — | EC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL1236524 | GALIDESIVIR | EC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL5270241 | — | EC50 | - | — | - | |
| CHEMBL5275463 | — | EC50 | > | 100000.0 | nM | - |