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Assay Detail

CHEMBL5260428

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human ALDH1A1 in presence of NAD+ by LC-MS/MS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Aldehyde dehydrogenase 1A1 (CHEMBL3577)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol.
Beers JL, Authement AK, Isoherranen N, Jackson KD.
ACS Med Chem Lett (2023) 14 : 614 -620
PubMed 37197460 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.99 6.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3276621 1 6.99

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3276621 IC50 = 102.0 nM 6.99