Assay Detail
Functional
CHEMBL5260485
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Cytotoxicity against human KOPT-K1 cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KOPTK1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Rational Design of Highly Potent and Selective Covalent MAP2K7 Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.55 | 5.55 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5284723 | — | — | 1 | 5.55 |
| CHEMBL553 | ERLOTINIB | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5284723 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL553 | ERLOTINIB | Activity | - | — | - |