Assay Detail
Toxicity
CHEMBL5260669
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Cytotoxicity against human PBMC cells assessed as reduction in cell viability measured after 72 hrs by CellTiter96 Aqueous One Solution cell proliferation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Biological evaluation of novel amidino substituted coumarin-benzazole hybrids as promising therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.79 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5284601 | — | — | 1 | 5.80 |
| CHEMBL5276739 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5284601 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL5276739 | — | IC50 | = | 1700.0 | nM | 5.77 |