Assay Detail
Functional
CHEMBL5260862
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Anti-inflammatory activity in human PBMC cells assessed as inhibition of LPS-induced TNF-alpha production
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Benzophenone: a ubiquitous scaffold in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.00 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL152208 | — | — | 1 | 8.40 |
| CHEMBL152767 | — | — | 1 | 8.40 |
| CHEMBL347496 | — | — | 1 | 8.40 |
| CHEMBL152596 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL152208 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL152767 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL347496 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL152596 | — | IC50 | = | 159.0 | nM | 6.80 |