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Assay Detail

CHEMBL5261114

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to CCR2 (unknown origin) assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

C-C chemokine receptor type 2 (CHEMBL4015)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structural Analysis of Chemokine Receptor-Ligand Interactions.
Arimont M, Sun SL, Leurs R, Smit M, de Esch IJP, de Graaf C.
J Med Chem (2017) 60 : 4735 -4779
PubMed 28165741 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 10.00 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2178578 VERCIRNON 3.0 1 10.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2178578 VERCIRNON Kd = 0.1 nM 10.00