Assay Detail
Toxicity
CHEMBL5261127
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against African green monkey COS7 cells assessed as inhibition of cell growth
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Chlorocebus aethiops |
| Cell Type | COS-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structural Analysis of Chemokine Receptor-Ligand Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.73 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5277802 | — | — | 1 | 8.05 |
| CHEMBL5268017 | — | — | 1 | 7.96 |
| CHEMBL5272687 | — | — | 1 | 7.82 |
| CHEMBL5270110 | — | — | 1 | 7.54 |
| CHEMBL5273480 | — | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5277802 | — | EC50 | = | 9.0 | nM | 8.05 |
| CHEMBL5268017 | — | EC50 | = | 11.0 | nM | 7.96 |
| CHEMBL5272687 | — | EC50 | = | 15.0 | nM | 7.82 |
| CHEMBL5270110 | — | EC50 | = | 29.0 | nM | 7.54 |
| CHEMBL5273480 | — | EC50 | = | 50.0 | nM | 7.30 |