Assay Detail
Binding
CHEMBL5261129
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Inhibition of CCR8 mutant (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural Analysis of Chemokine Receptor-Ligand Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.72 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5268017 | — | — | 1 | 8.00 |
| CHEMBL5277802 | — | — | 1 | 8.00 |
| CHEMBL5272687 | — | — | 1 | 7.80 |
| CHEMBL5270110 | — | — | 1 | 7.50 |
| CHEMBL5273480 | — | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5268017 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5277802 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5272687 | — | IC50 | = | 15.85 | nM | 7.80 |
| CHEMBL5270110 | — | IC50 | = | 31.62 | nM | 7.50 |
| CHEMBL5273480 | — | IC50 | = | 50.12 | nM | 7.30 |