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Assay Detail

CHEMBL5261134

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Alpha-glucosidase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Maltase-glucoamylase (CHEMBL2074)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties.
Selvam C, Jordan BC, Prakash S, Mutisya D, Thilagavathi R.
Eur J Med Chem (2017) 128 : 219 -236
PubMed 28189086 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL30707 COUMESTROL 1 5.22
CHEMBL5279690 1 -
CHEMBL5269655 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL30707 COUMESTROL IC50 = 6000.0 nM 5.22
CHEMBL5279690 IC50 = 128100.0 nM -
CHEMBL5269655 IC50 = 174200.0 nM -