Assay Detail
Binding
CHEMBL5262373
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Binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BROMOscan assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.46 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5282240 | — | — | 1 | 5.46 |
| CHEMBL5289762 | — | — | 1 | - |
| CHEMBL5270178 | — | — | 1 | - |
| CHEMBL5268484 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5282240 | — | Kd | = | 3500.0 | nM | 5.46 |
| CHEMBL5289762 | — | Kd | > | 10000.0 | nM | - |
| CHEMBL5270178 | — | Kd | > | 10000.0 | nM | - |
| CHEMBL5268484 | — | Kd | > | 10000.0 | nM | - |