Assay Detail

CHEMBL5262828

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Toxicity

Cytotoxicity against African green monkey Vero cells

ChEMBL ↗

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Target

Vero (CHEMBL391) ↗

Open DB target context

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Primary target Vero

CHEMBL391

Anchored from Assay target.

Protein identity Vero

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Toxicity
Organism	Chlorocebus sabaeus
Cell Type	Vero
Confidence	1 — Organism
Curated By	Autocuration

Target

Vero (CHEMBL391) ↗

Type	CELL-LINE
Organism	Chlorocebus sabaeus

Publication

Drug development against tuberculosis: Impact of alkaloids.

Mishra SK, Tripathi G, Kishore N, Singh RK, Singh A, Tiwari VK.
Eur J Med Chem (2017) 137 : 504 -544
PubMed 28628823 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.85	6.85

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL340160	ASCIDIDEMIN	—	1	6.85

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL340160	ASCIDIDEMIN	IC50	=	140.0	nM	6.85