Assay Detail

CHEMBL5263063

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Binding

Inhibition of Trypanosoma MetRS

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Trypanosoma
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Polyamine-based analogs and conjugates as antikinetoplastid agents.

Jagu E, Pomel S, Pethe S, Loiseau PM, Labruère R.
Eur J Med Chem (2017) 139 : 982 -1015
PubMed 28886510 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5288670	—	—	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5288670	—	Ki	=	2.0	nM	8.70