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Assay Detail

CHEMBL5263238

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Bacillus anthracis anthrax lethal factor using MAPKKide as substrate incubated for 30 mins by fluorescence plate reader analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacillus anthracis
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lethal factor (CHEMBL4372)
Type SINGLE PROTEIN
Organism Bacillus anthracis

Publication

5-Ene-4-thiazolidinones - An efficient tool in medicinal chemistry.
Kaminskyy D, Kryshchyshyn A, Lesyk R.
Eur J Med Chem (2017) 140 : 542 -594
PubMed 28987611 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2348824 1 5.00
CHEMBL211933 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2348824 IC50 = 10000.0 nM 5.00
CHEMBL211933 IC50 = 10000.0 nM 5.00