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Assay Detail

CHEMBL5263250

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human COX-2 using [14C]arachidonic acid as substrate incubated for 1 mins by radiometric HPLC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prostaglandin G/H synthase 2 (CHEMBL230)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

5-Ene-4-thiazolidinones - An efficient tool in medicinal chemistry.
Kaminskyy D, Kryshchyshyn A, Lesyk R.
Eur J Med Chem (2017) 140 : 542 -594
PubMed 28987611 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.77 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL15791 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL15791 IC50 = 1700.0 nM 5.77