Assay Detail
Binding
CHEMBL5264073
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of 3[H]BTX from rat cerebral cortex sodium channel assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Cerebral cortex |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.74 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3039733 | CROBENETINE | 2.0 | 1 | 7.37 |
| CHEMBL5286162 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3039733 | CROBENETINE | Ki | = | 43.0 | nM | 7.37 |
| CHEMBL5286162 | — | Ki | = | 789.0 | nM | 6.10 |