Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5264993

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at human PPARalpha
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peroxisome proliferator-activated receptor alpha (CHEMBL239)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.
Yang Y, Zhao Y, Li W, Wu Y, Wang X, Wang Y, Liu T, Ye T, Xie Y, Cheng Z, He J, Bai P, Zhang Y, Ouyang L.
Eur J Med Chem (2020) 197 : 112311 -112311
PubMed 32339855 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.56 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4091374 LANIFIBRANOR 3.0 1 5.82
CHEMBL295416 PIRINIXIC ACID 2.0 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4091374 LANIFIBRANOR EC50 = 1500.0 nM 5.82
CHEMBL295416 PIRINIXIC ACID EC50 = 5000.0 nM 5.30