Assay Detail
Binding
CHEMBL5264995
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at Gal4-fused PPARalpha LBD (unknown origin) transfected in human HepG2 cells assessed as transcriptional activation incubated for 24 hrs by luciferase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL239) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL247951 | PEMAFIBRATE | 4.0 | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL247951 | PEMAFIBRATE | EC50 | = | 1.0 | nM | 9.00 |