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Assay Detail

CHEMBL5264998

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at PPARgamma (unknown origin) assessed as transcriptional activation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peroxisome proliferator-activated receptor gamma (CHEMBL235)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.
Yang Y, Zhao Y, Li W, Wu Y, Wang X, Wang Y, Liu T, Ye T, Xie Y, Cheng Z, He J, Bai P, Zhang Y, Ouyang L.
Eur J Med Chem (2020) 197 : 112311 -112311
PubMed 32339855 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.76 6.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3707395 ELAFIBRANOR 4.0 1 6.76

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3707395 ELAFIBRANOR EC50 = 175.0 nM 6.76