Assay Detail
Functional
CHEMBL5265033
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Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability celltiter-Glo assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Current scenario of indole derivatives with potential anti-drug-resistant cancer activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.23 | 5.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5267163 | — | — | 1 | 5.56 |
| CHEMBL5282059 | — | — | 1 | 5.14 |
| CHEMBL535 | SUNITINIB | 4.0 | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5267163 | — | IC50 | = | 2750.0 | nM | 5.56 |
| CHEMBL5282059 | — | IC50 | = | 7250.0 | nM | 5.14 |
| CHEMBL535 | SUNITINIB | IC50 | = | 10140.0 | nM | 4.99 |