Assay Detail
Binding
CHEMBL5265199
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CA9
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advancements in the development of bioactive pyrazoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.17 | 8.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5274534 | — | — | 1 | 8.26 |
| CHEMBL5279517 | — | — | 1 | 8.26 |
| CHEMBL5273842 | — | — | 1 | 8.26 |
| CHEMBL5291363 | — | — | 1 | 8.26 |
| CHEMBL5286421 | — | — | 1 | 8.26 |
| CHEMBL5280722 | — | — | 1 | 8.26 |
| CHEMBL20 | ACETAZOLAMIDE | 4.0 | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5274534 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL5279517 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL5273842 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL5291363 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL5286421 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL5280722 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL20 | ACETAZOLAMIDE | Ki | = | 25.0 | nM | 7.60 |