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Assay Detail

CHEMBL5265229

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human MAO-B by spectrofluorimetric analysis
ChEMBL ↗
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent advancements in the development of bioactive pyrazoline derivatives.
Nehra B, Rulhania S, Jaswal S, Kumar B, Singh G, Monga V.
Eur J Med Chem (2020) 205 : 112666 -112666
PubMed 32795767 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 16 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5269241 — — 1 6.70
CHEMBL5283319 — — 1 6.70
CHEMBL5276967 — — 1 6.70
CHEMBL5272518 — — 1 6.70
CHEMBL5291452 — — 1 6.70
CHEMBL5280524 — — 1 6.70
CHEMBL5272772 — — 1 6.70
CHEMBL5271570 — — 1 6.70
CHEMBL5268306 — — 1 6.70
CHEMBL5273835 — — 1 6.70
CHEMBL5284012 — — 1 6.70
CHEMBL5275680 — — 1 6.70
CHEMBL5290358 — — 1 6.70
CHEMBL5284128 — — 1 6.70
CHEMBL5282135 — — 1 6.70
CHEMBL5270226 — — 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5269241 — Ki = 200.0 nM 6.70
CHEMBL5283319 — Ki = 200.0 nM 6.70
CHEMBL5276967 — Ki = 200.0 nM 6.70
CHEMBL5272518 — Ki = 200.0 nM 6.70
CHEMBL5291452 — Ki = 200.0 nM 6.70
CHEMBL5280524 — Ki = 200.0 nM 6.70
CHEMBL5272772 — Ki = 200.0 nM 6.70
CHEMBL5271570 — Ki = 200.0 nM 6.70
CHEMBL5268306 — Ki = 200.0 nM 6.70
CHEMBL5273835 — Ki = 200.0 nM 6.70
CHEMBL5284012 — Ki = 200.0 nM 6.70
CHEMBL5275680 — Ki = 200.0 nM 6.70
CHEMBL5290358 — Ki = 200.0 nM 6.70
CHEMBL5284128 — Ki = 200.0 nM 6.70
CHEMBL5282135 — Ki = 200.0 nM 6.70
CHEMBL5270226 — Ki = 200.0 nM 6.70