Assay Detail
Binding
CHEMBL5265250
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Antagonist activity against LuxPQ quorum sensing system in Vibrio harveyi MM32 assessed as inhibition of luminescence intensity incubated for 3 to 4 hrs by luminescence microplate reader analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Vibrio harveyi |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Current advances in Vibrio harveyi quorum sensing as drug discovery targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.27 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1824170 | — | — | 1 | 5.40 |
| CHEMBL1824171 | — | — | 1 | 5.40 |
| CHEMBL1824169 | — | — | 1 | 5.30 |
| CHEMBL500339 | — | — | 1 | 5.22 |
| CHEMBL1824168 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1824170 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1824171 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1824169 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL500339 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL1824168 | — | IC50 | = | 9000.0 | nM | 5.05 |