Assay Detail
Binding
CHEMBL5316764
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human RXRbeta LBD and measured for 180 sec by ITC analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXRα, RXRβ, and RXRγ.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.46 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5415488 | — | — | 1 | 5.52 |
| CHEMBL5418573 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5415488 | — | Kd | = | 3000.0 | nM | 5.52 |
| CHEMBL5418573 | — | Kd | = | 4000.0 | nM | 5.40 |