Assay Detail
Binding
CHEMBL5317802
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Binding affinity to Clostridioides difficile-specific DNA adenine methyltransferase PDB 7RFL by MicroCal PEAQ ITC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Clostridioides difficile |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Systematic Design of Adenosine Analogs as Inhibitors of a <i>Clostridioides difficile-</i>Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.20 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3087498 | — | — | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3087498 | — | Kd | = | 6300.0 | nM | 5.20 |