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Assay Detail

CHEMBL5317877

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of alpha glucosidase (unknown origin) measured after 60 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Alpha glucosidase (CHEMBL3833502)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species.
Sidhom PA, El-Bastawissy E, Ibrahim MAA, Shawky AM, Salama A, El-Moselhy T.
J Med Chem (2023) 66 : 991 -1010
PubMed 36584305 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.24 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5414025 1 5.35
CHEMBL404271 ACARBOSE 4.0 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5414025 IC50 = 4480.0 nM 5.35
CHEMBL404271 ACARBOSE IC50 = 7400.0 nM 5.13