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Assay Detail

CHEMBL5320531

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to HCoV-NL63 MPro assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human coronavirus NL63
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective.
Pozzi C, Vanet A, Francesconi V, Tagliazucchi L, Tassone G, Venturelli A, Spyrakis F, Mazzorana M, Costi MP, Tonelli M.
J Med Chem (2023) 66 : 3664 -3702
PubMed 36857133 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.95 4.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1230135 1 4.95

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1230135 Ki = 11300.0 nM 4.95