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Assay Detail

CHEMBL5320548

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-1 infected in African green monkey Vero E6 cells expressing TMPRSS2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome-related coronavirus
Cell Type Vero E6
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV (CHEMBL4303836)
Type ORGANISM
Organism Severe acute respiratory syndrome-related coronavirus

Publication

Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective.
Pozzi C, Vanet A, Francesconi V, Tagliazucchi L, Tassone G, Venturelli A, Spyrakis F, Mazzorana M, Costi MP, Tonelli M.
J Med Chem (2023) 66 : 3664 -3702
PubMed 36857133 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.68 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2435614 1 6.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2435614 EC50 = 210.0 nM 6.68