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Assay Detail

CHEMBL5320560

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against pseudo SARS-CoV-2 virus
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective.
Pozzi C, Vanet A, Francesconi V, Tagliazucchi L, Tassone G, Venturelli A, Spyrakis F, Mazzorana M, Costi MP, Tonelli M.
J Med Chem (2023) 66 : 3664 -3702
PubMed 36857133 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.49 9.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL91704 K-777 2.0 1 9.17
CHEMBL2367892 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL91704 K-777 IC50 = 0.68 nM 9.17
CHEMBL2367892 IC50 = 1600.0 nM 5.80